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Thus, targeting TRPM2 in microglia may offer a promising strategy to modulate their activity and, in pathological contexts, could serve as a potential therapeutic alternative to treat conditions with a neuroinflammatory aspect, which is the case of neurological diseases

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A fixed mass of peptide reconstituted in a larger diluent volume yields a lower concentration per unit volume, and vice versa

Food-grade glutathione is suitable for injection. Food and supplement ingredients are manufactured for ingestion rather than sterile administration

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The first identification of parthanatos was in 2006 when hyperglycemia was found to increase mitochondrial ROS production and DNA damage in diabetes models [137]